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Improving Drug Delivery and Minimising Side Effects through Nanobody/Antibody Engineering

A comparative evaluation of advanced delivery platforms to improve bioavailability and reduce adverse effects

Projektbeskrivelse

This project aims to explore how existing drugs with significant therapeutic potential but notable side effects could be improved via targeted delivery using nanobodies or monoclonal antibodies. A specific focus will be placed on drugs already on the market, where bioavailability issues or off-target toxicity are limiting their effectiveness. The project will involve a literature-based review and/or modelling of delivery strategies (e.g. antibody-drug conjugates, nanobody carriers, PEGylation), with the goal of proposing novel optimisations that increase therapeutic precision.

Forretningsmæssig værdi

For pharmaceutical companies, optimising delivery means better efficacy and lower development costs for next-generation versions of existing assets. It supports lifecycle management, increases patient compliance, and may open up new indications. The project also offers insights that could accelerate reformulation strategies.

Emne motivation

I’m fascinated by the combination of molecular engineering and clinical application. The idea of taking a molecule that already works and making it smarter, safer, and more patient-friendly captures my interest and aligns closely with my future goals in Pharmatechnology.

Hvorfor samarbejde med os

I bring a strong academic foundation in immunology, bioinformatics, biochemistry, and drug development, alongside a natural curiosity and a detail-oriented mindset. I work with structure and clarity, love challenging questions, and thrive when combining science with practical problem-solving. You’ll get someone who shows up prepared, takes initiative, and genuinely wants to contribute.

Projektforsker #1

Talent bio

I have just completed my fourth semester in Life Science and Technology at the Technical University of Denmark, where I specialise in technical biomedicine. I plan to continue directly into the MSc in Pharmatechnology in 2026. Through my studies, I have gained hands-on experience and theoretical knowledge in biochemistry, organic chemistry, molecular biology, immunology, bioinformatics, drug development, laboratory methods, and statistics. In my fifth semester, I will be going on academic exchange, where I plan to focus further on metabolic pathways and developmental biology — areas that increasingly fascinate me.

Passion og motivation

I am driven by the desire to create meaningful change in healthcare — to make life better and treatments more accessible. My passion for biotechnology and mathematics led me to Life Science and Technology, where I now feel confident that I want to help develop future therapies that are both innovative and equitable. I am especially inspired by the discovery of new metabolic pathways and their potential as therapeutic targets. I'm also deeply interested in developing long-term solutions for allergies — a growing global challenge that I believe deserves greater attention. Whether in drug discovery, formulation, or translational science, I want to contribute to impactful, real-world solutions.

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